Detailed Research Experience


Doctoral Dissertation Research — Moffitt Cancer Center (2020–2025) **Location:** Tampa, FL, USA **Title:** *The Only Constant Is Change: The Role of Genetic Diversification in Cancer and Beyond* **PIs:** David Basanta, PhD; Andriy Marusyk, PhD **Committee members:** Noemi Andor, PhD; Philipp Altrock, PhD; Joel Brown, PhD **Defense chair:** Jacob Scott, MD, PhD **Key contributions:** - Developed, analyzed, and interpreted Agent-Based Models (ABM) of mutation-driven tumor evolution — *Published in PNAS*: <https://doi.org/10.1073/pnas.2427070122> - Collaborated with experimental biologists to validate an *in silico* model with an *in vitro* NSCLC model (with Pragya Kumar, Marusyk lab, Moffitt Cancer Center). - Developed and calibrated an ABM to study adaptive limits of ecDNA during tumor progression (with Andrea Ventura, MD, PhD, Ventura lab, MSKCC). - Developed and calibrated a pharmacometric model of Lorlatinib metabolic conversion using mouse and patient data (with Pragya Kumar, Marusyk lab, Moffitt Cancer Center). - Collaborated with biologists, clinicians, and mathematical oncologists through IMO workshops (2022–2024). - Prepared manuscripts and presented work at international conferences.

Research Associate — University of Michigan Medical School (2018–2020) **Location:** Ann Arbor, MI, USA **PI:** Santiago Schnell, D.Phil. **Key contributions:** - Developed and evaluated a mathematical model for autocatalytic enzyme reaction kinetics; created illustrations and co-wrote the manuscript — *Published in SIAM*: <https://doi.org/10.1137/20M135073X> - Collaborated on statistical models for cyst fragmentation during oocyte and testis formation — *Published in PNAS*: <https://www.pnas.org/doi/10.1073/pnas.2219683120> - Performed statistical analysis of 50k+ SABIO-RK database entries to assess reproducibility of biochemical constants.

Master’s Thesis Research — KAIST & DTU (2017–2018) **Locations:** Daejeon, South Korea & Kgs. Lyngby, Denmark **Title:** *Detecting Causality in Oscillatory Systems* **PIs:** Jae Kyoung Kim, PhD (KAIST); Lasse Engbo Christiansen, PhD (DTU) **Key contributions:** - Evaluated accuracy and sensitivity of mathematical algorithms for detecting causality in oscillatory time series using: 1. Stochastic simulations of mammalian circadian rhythms 2. Neural activity recordings from the mammalian Suprachiasmatic Nucleus

Industry Collaboration — Westrup ApS & DTU (2016) **Location:** Kgs. Lyngby, Denmark **Title:** *Optimization of Vibrations in Sorting Machines* **PI:** Poul Hjorth, PhD (DTU) **Key contributions:** - Modeled seed-sorting machine design to quantify harmful vibrations. - Proposed optimization strategies to reduce vibration levels.

Bachelor’s Thesis Research — Technical University of Denmark (2015) **Location:** Kgs. Lyngby, Denmark **Title:** *Modeling of Chemotaxis and Aggregation of Biological Cells* **PI:** Mads Peter Soerensen, PhD **Key contributions:** - Developed, implemented, and simulated 2D PDE models for chemotaxis and cellular aggregation.

Undergraduate Research Project — Oregon State University (2015) **Location:** Corvallis, Oregon **PI:** Malgorzata Peszynska, PhD **Key contributions:** - Developed and simulated 2D PDE models for chemotaxis of *Staphylococcus aureus*.